Inventor Flint Lockwood and his friends have saved the world from the food storm created by the "Flint Lockwood Diatonic Super Mutating Dynamic Food Replicator" (FLDSMDFR) but this has left their island home town of Swallow Falls covered in food. Super-inventor Chester V, the CEO of Live Corp and Flint's childhood idol, offers his company's services to clean the island and helps to relocate the population to nearby San Franjose, California. Chester also invites Flint to work at Live Corp.