Despite an approaching winter storm a near-empty airliner takes off from London for New York City. One by one the passengers begin to disappear, while one passenger who frequents the route notices the plane has turned whereas it should be flying straight. Soon it is discovered that the pilots are dead and that the plane is on autopilot; and it is revealed that two on board are hijackers who have murdered the pilots to take control of the plane. The passengers who disappeared were killed when they witnessed parts of the hijacking.