Manji is a samurai on the run after killing his corrupt lord and his bodyguards, which included the husband of his sister Machi. As a result of her husband's death at the hands of her brother, Machi lost her mind from grief. Rather than commit ritual suicide as honor dictates, Manji chose to care for his now insane sister. While on the run, Manji encounters an 800-year-old nun named Yaobikuni who questions him about his decisions distracting him from his sister who runs off. Machi is found being held hostage by a group of rōnin out for the bounty on Manji's head. The rōnin's leader demands Manji disarm himself, implying that he would kill Machi if he did not. When Manji does comply with the rōnin's demands, the rōnin proceeds to kill Machi anyway. In retaliation Manji kills every member of the group, but is mortally wounded. As there was nothing left to live for, he accepts his death, but Yaobikuni implants "sacred bloodworms" into his body, which heal him.