In 1899, an Oxford University professor demonstrates a case of female hysteria, Eliza Graves, before his class. Though she protests that she is sane, the professor points out that all mental patients claim to be sane, much as all criminals claim to be innocent. The professor advises his students to believe nothing they hear and only half of what they see. Later, a young man arrives at Stonehearst Asylum, where he desires to take up residency. A group of armed men led by Mickey Finn allow him entry. Finn escorts him to the office of the superintendent, Dr. Silas Lamb, where the young doctor introduces himself as Dr. Edward Newgate from Oxford. Although Lamb was not expecting him, he welcomes the help of an Oxford-educated doctor.