Milo (Hader) writes a suicide note and cuts his wrists. Meanwhile, Maggie (Wiig) is in her bathroom preparing to swallow a handful of pills, but is interrupted by a call from a hospital informing her that her brother – whom she hasn't seen in 10 years – has unsuccessfully attempted suicide. Maggie visits Milo in the hospital in Los Angeles, and suggests that he come to stay with her in their hometown of Nyack, New York for a while; he reluctantly agrees. Milo meets Maggie's gregarious husband Lance (Luke Wilson), who tells Milo he and Maggie are trying to have a baby. This surprises Milo, as Maggie never expressed wanting children. Milo reacquaints himself with the town, and observes Rich (Burrell), a middle-aged man working in a bookstore. Meanwhile, Maggie is taking scuba lessons, and having sex with the instructor, Billy (Holbrook).