In the spring of 1941, American journalist Michael Gordon (George Sanders) and his colleague, William Chalmers (Robert Anderson (actor born 1923)), arrive in Damascus. When Chalmers is murdered, Gordon sets out to find out why. He is helped along by glamorous secret agent Yvonne (Virginia Bruce), who is on the trail of a group of Nazi saboteurs. Intrigue centers around the actions of Josef Danesco (Gene Lockhart) who offers to sell information, as well as French diplomatic official Andre Leroux (André Charlot) and Eric Latimer (Alan Napier), the owner of the Hotel International, both suspected of having connections with the Nazis.