A Miami businessman, John Stone, receives a parcel from England containing two old bottles of Slivovitz fruit brandy from his recently deceased ancestor, and after drinking both bottles, becomes a vampire. Stone uses his newfound vampire powers to keep his wife, Helena, in a trance as he travels to England to kill the descendents of Abraham Van Helsing that murdered Count Dracula. Meanwhile, Helsing's distant relative, Howard Helsing, pursues Stone with the intent to put the reborn vampire to rest for good.