The film begins on "Friday, April 17" at 4P.M. in Venice, California. Huckleberry P. Jones, local pimp, narcotics peddler and slumlord, enters a vacant house that he owns. While stashing heroin in the basement, he stumbles upon a mysterious door and enters it, falling into the Sixth Dimension, from which he promptly escapes. After retrieving the heroin, he sells the house to the Hercules family. On their way to school, Frenchy Hercules and her brother Flash have a conversation with Squeezit Henderson, who tells them that, while being violently beaten by his mother, he had a vision of his transgender sister René, who had fallen into the Sixth Dimension through the door in the Hercules' basement.