''Lewis and Clark and George'' opens with Salvator Xuereb (playing Lewis) and Dan Gunther (Clark) at a water tank site wearing prison jump suits. The scene is desert Scrubland and the two state prison escapees have just located a buried metal box with a loaded revolver, treasure map, and Cuban cigars. A road trip begins as the two hike off through the desert to find the treasure, eventually joined by Rose McGowan (George).