The family of a wealthy woman named Anastasia "Granny" Gargoli (Stella Stevens) wants her to die so they can inherit her insurance. Granny is given an eternal life potion by a mysterious preacher Namon Ami (Luca Bercovici). Although the preacher admonishes her not to take it in sunlight, Granny ignores him and drinks it in broad daylight. She melts into nothing but arises from a grave as a vampire-like monster. Granny starts killing her family to prevent them from inheriting her Wealth. It is up to Kelly (Shannon Whirry) and Amy (Samantha Hendricks) to stop the blood hungry, vampire-like granny.