In the near future, Harley-Davidson (Mickey Rourke) travels from Texas to Burbank, California to reconnect with his old friend Robert "Marlboro Man" Anderson (Don Johnson) at their old haunt; Rock N' Roll Bar & Grille. Their mutual friend Jack Daniel's (Big John Studd) holds animosity towards Harley over an affair he and his now-wife Lulu (Vanessa Williams) had years prior. The bar has fallen on hard times, and the Great Trust bank has threatened foreclosure, planning to demolish the building to make way for a skyscraper. Harley and Robert convince Jack to help them rob one of the Bank's armoured cars in order to collect the funds necessary to renew the building's lease. The robbery mostly goes off without a hitch, but the trio are intercepted by a group of security agents who almost foil their getaway. Upon escaping, they discover the loot they stole from the van contains not money, but a new, experimental street drug called "Crystal Dream."