After the events in the previous film Riley (Matt Mercer (actor)) has begun showing symptoms of the same illness that caused Samantha (Najarra Townsend) to turn into a zombie. Panicking, Riley decides that he needs to track down the person who first infected Samantha, BJ (Morgan Peter Brown), in the hopes of gaining a cure. However BJ has his own agenda, as he is more than willing to continue to spread the disease to other victims.