The episodic narrative, consisting of several individual skits threaded together, focused on an ailing Mother Nature (Bette Midler), who falls from the sky and faints, and is rushed to the hospital where she is attended to by Doogie Howser, M.D. (Neil Patrick Harris) and two other doctors (James Brolin and Dana Delany). This special is watched by a married couple named Vic (Danny DeVito) and Paula (Rhea Perlman), and features a host of contemporary celebrities and characters, including Bugs Bunny, the Muppets, and E.T.