Ken Stott plays Eddie McKenna, a double-glazing salesman who moonlights as a DJ for hospital radio in a Scottish mental asylum - St Judes. He nurtures close friendships with the patients there including Francine, a self-harmer and Campbell, a manic depressive, with whom he shares a dream to make it onto the commercial radio scene. Campbell's inspired antics promise to bring the pair closer to their aim, but the pressures of life outside of the hospital begin to tell on Eddie. A vindictive colleague leads his small-minded boss to ban his activities at 'the looney-bin' and his eccentric grandmother returns suddenly to Lithuania leaving him peniless and alone. Eddie finds himself drawn to the troubled Francine, but when the radio is threatened with closure it is to another 'wee friend' he turns for comfort as slowly we watch the roles reverse.