High school student Shin Kanzato with his little brother Jun, meet with their elder brother Ryou, who is the chief of the Ayanagi City Police, again after ten years. At that time, a series of strange incidents happen in Ayanagi City such as the crew of a submarine that suddenly disappears while in their submarine, or a spiritless symptom which disturbs the world after ten years, or the case of the inside out corpse where a student took on a cruel appearance. Ryou tracks down the organization behind the string of incidents, and having become involved in the incidents, Shin awakens the "Persona."