Eddie Morra is a struggling author in New York City. His girlfriend Lindy, frustrated with his lack of progress, breaks up with him. Eddie encounters Vernon, the brother of his ex-wife Melissa, who gives Eddie a sample of a new nootropic called NZT-48. On the drug, Eddie discovers he has acquired perfect recollection of everything he has ever read and refined his interpersonal skills. His new power enables him to make significant progress on his book.