Duetto takes place in Italy, in 1965, and tells the story of the encounter between Cora, a Brazilian teenager, and the famous and controversial Italian singer Marcello Bianchini. But the story begins in São Paulo. After the tragic death of her father in a car accident, Cora travels with her grandmother, Lucia, to her hometown in Apulia. Between the family past, the dramas and stories of the small Italian town, Cora will make her way to maturity and adulthood.