A former CIA agent and ex-Special Forces member Dean Cage (Wesley Snipes), is in a rehab program, haunted by a botched mission in Bosnia which resulted in the execution of his best friend Scott (Cristian Solimeno). While in a restaurant waiting for his girlfriend, Baltimore Police Detective Amy Knight (Jacqueline Obradors), who happens to be Scott's sister, he is mistakenly believed to be a CIA agent involved with a stolen military experimental truth serum. He is abducted by the real thieves and injected with the drug, which makes him relive the moments from the failed Bosnian mission and not able to discern who are his allies and who are his enemies. Amy has six hours to find the antidote and save Dean's life.