A reporter is killed in his car on his way to work. Inspector Kras gets a call from his informant Peter Cornelius, a blind fortuneteller, who had a vision of the crime but not the perpetrator. Meanwhile, Henry Travers, a rich American industrialist, checks into the Luxor Hotel, which has been outfitted by the Nazis during World War II to spy on people in every room. He becomes involved with Marian Menil, who is being threatened by her evil club-footed husband, Hieronymus B. Mistelzweig, purportedly a salesman, who is also a guest in the hotel and always seems to be lurking about. These disparate characters eventually get together to solve what appears to be the re-emergence of the long-dead Dr. Mabuse.