Set in the city of Philadelphia and famed Overbrook High School (Philadelphia), ''Brotherly Love'' follows star high school basketball player Sergio Taylor (Hill) as he struggles navigating the fame that comes with being a star athlete. Sergio's older brother June (Cory Hardrict) saw his own basketball dreams fade away when he turned to the streets to provide for his family after the death of their father. Sergio's twin sister Jackie (Keke Palmer) saw her ambitions of having a music career side tracked after unexpectedly falling in love with (Quincy (Chris)).