John and Dean are two sheltered happy-go-lucky brothers who want nothing more than to please their ailing father. Deciding a grandson will do the trick, the clueless boys set out to find a woman who can give them a baby. Finding Janine on Craigslist, they find the woman of their dreams, artificially inseminating her and spending the next nine months on a roller coaster of life, facing romantic and parental challenges along the way that are no match for their sunny attitude.