Marley Corbett is a quickwitted, care-free ad executive living in New Orleans, who embraces her easy going attitude, shuns any major responsibilities, and gains support and strength from a close circle of friends. She also enjoys casual dating and refuses to fall in love. Marley's close friend notices that she looks drained. After an appointment, Marley is told by Dr. Julian Goldstein that she has terminal cancer. He is deeply impressed by the way Marley accepts the news with humour and dignity. While under anesthetic, God appears to Marley in heaven and asks her to make three wishes. She chooses to fly, to win a million dollars (not tax free), and a third that is later revealed.