After the events of the Mickey Mouse Clubhouse episode Minnie's Bow-tique, Minnie’s Bow-Toons follows the adventures of Minnie Mouse and her best friend Daisy Duck and their new friend a talking Cuckcoo-Clock-Bird named Cuckoo-Loca as they run Minnie’s Bow-Tique, a specialty shop below Minnie's new Apartment that is stocked only with colorful bows and bowties.