De Ijazat Jo Tu story revolves around the love story of Sarmad (Farhan Saeed) and Ayla (Sohai Ali Abro). While Ayla comes from a middle-class background with a doting family, Sarmad comes from a rich background but is distant from his father due to his father's busy schedule. His stepmother doesn't care about him nor does his stepbrother. Ayla's entry into Sarmad's life is a blessing for him and he feels his loneliness disappearing. Sarmad and Ayla get married, much to the dismay of his stepmother and are forced to move into their own home due to her disapproval (despite having support from her family and his father).