After the death of his wife and daughter in a plane crash, a newspaper reporter named Joe Carpenter discovers that the crash may have been related to a nefarious scientific experiment involving children. A woman, Rose Tucker, who claims she was a survivor of the crash, approaches at his wife's grave. This leads into a plot by the Quartermass organization to capture her and a young girl she is protecting - the girl has the powers to heal and to transport. A villainous killer named Victor Yates and a young boy who can control minds from a distance lead the attack.