The time is the end of Samurai era (Edo) and the new Meiji government is founded in Japan. Legend has it that a gigantic snake “Orochi” which has a special power revives every 300 years and brings harm to the country. Three young brothers, Tenka, Soramaru, Chutaro who are the guardian of Kumou shrine stand up to prevent the “Orochi” from coming back to life along with the Meiji government’s army to save the country. However, the evil Fuma ninja clan attempts to use the power of “Orochi” in order to weaken the government letting the snake to attack and eventually taking over Japan.