A violent slaughter occurs in an abandoned house in Louisiana where three college students are found dead. Detective Mark Lewis (Frank Grillo) examines the crime scene and finds a shocked survivor, John (Dustin Milligan), before calling reinforcements. Several police cars then arrive at the house alongside an ambulance with psychologist, Dr. Elizabeth Klein (Maria Bello). She talks to John, who tells her that a seance performed in the house called the attention of many spirits, including one he identified as his mother, and that two of the group members - his pregnant girlfriend, Michelle (Cody Horn), and her ex-boyfriend, Bryan (Scott Mechlowicz) - are still missing.