Three estranged, Depression (mood) friends—Adam Yates, who was dumped by his girlfriend; henpecked husband Nick Webber-Agnew working a dead-end job; and Lou Dorchen, who is a party animal in his 40s—reconnect when Lou is hospitalized for carbon monoxide poisoning. To cheer him up, Adam and Nick arrange for Lou to join them at Kodiak Valley Ski Resort, where the three enjoyed fun times in their youth; Adam's Recluse nephew Jacob tags along. During a night of heavy drinking in their hotel room's hot tub, the four douse the console with an illegal Russian energy drink called "Chernobly".