Julia Streak (Louisa Krause) is a troubled, antipsychotic-dependent young woman who takes a job as a night guard at a grand but abandoned apartment complex so she can support her daughter, Clara. She is accepted by master keeper Dixon Boothe (Ezra Knight) and introduced to the only other security guard for the complex, the rude paraplegic Dennis Cooper (Jason Patric), who has been working at the complex since it opened. While patrolling, Julia hears whispers from Room 441, whose access is blocked by a locked door. Cooper denies that there is anything unusual behind the door, claiming that the owners left the room unfinished.